Nature, Published online: 24 February 2026; doi:10.1038/s41586-026-10294-0
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Nearly £50m of taxpayers' money has been paid by the NHS to an outsourced firm assessing claims of medical harm caused by vaccines, the BBC has found.
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The problem gets worse in pipelines. When you chain multiple transforms — say, parse, transform, then serialize — each TransformStream has its own internal readable and writable buffers. If implementers follow the spec strictly, data cascades through these buffers in a push-oriented fashion: the source pushes to transform A, which pushes to transform B, which pushes to transform C, each accumulating data in intermediate buffers before the final consumer has even started pulling. With three transforms, you can have six internal buffers filling up simultaneously.